Claesson H, Bárány E
Acta Physiol Scand. 1978 Apr;102(4):394-8. doi: 10.1111/j.1748-1716.1978.tb06086.x.
Pigmented rats were kept under different light regimens for 1--20 days. Supramaximal light was used. The response of the iris sphincter in enucleated eyes with their cornea intact was tested in vitro. Pilocarpine at 6 X 10(-5) M was used as a standard stimulus. In agreement with previous authors there was a marked difference between constant light treated (subsensitive) eyes and dark treated (supersensitive) ones. Animals pretreated to reach maximal sub- and supersensitivity and then shifted to the opposite regimen, showed that reversal was a gradual process starting within a few hours. Full reversal had not been reached at 72 h. The two curves of sensitivity vs time intersected around 24 h. The time constants of the two curves were approximately equal. Light regimens using intermittent light shifting every 1, 3, 6 or 12 h gave intermediate results.
将有色大鼠置于不同光照方案下1至20天。采用超最大光照。在体外测试角膜完整的摘除眼球中虹膜括约肌的反应。使用6×10⁻⁵ M的毛果芸香碱作为标准刺激物。与先前的作者一致，持续光照处理（亚敏感）的眼睛和黑暗处理（超敏感）的眼睛之间存在明显差异。预先处理以达到最大亚敏感性和超敏感性，然后转换到相反方案的动物表明，逆转是一个从数小时内开始的渐进过程。在72小时时未达到完全逆转。两条敏感性与时间的曲线在约24小时处相交。两条曲线的时间常数大致相等。每1、3、6或12小时进行一次间歇光照转换的光照方案给出了中间结果。
