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缺血性心脏病死亡病例中心肌金属含量的差异。

Differences in metal content of the heart muscle in death from ischemic heart disease.

作者信息

Chipperfield B, Chipperfield J R

出版信息

Am Heart J. 1978 Jun;95(6):732-7. doi: 10.1016/0002-8703(78)90503-3.

DOI:10.1016/0002-8703(78)90503-3
PMID:655086
Abstract

In a group of patients dying suddenly from ischemic heart disease, the uninfarcted heart muscle contained significantly lower concentrations of magnesium, iron, and potassium and a significantly higher concentration of calcium than the heart muscle from a group of normal controls and a group of patients dying more than three months after a coronary thrombosis. The late death group had significantly lower concentrations of manganese and copper than the normal group, and a slight decrease in magnesium concentration which was probably significant. There was no significant difference in the sodium concentration between the three groups. The results are discussed in relation to the increased death rate from ischemic heart disease in areas with soft drinking water, and possible dietary deficiencies in mineral salts.

摘要

在一组因缺血性心脏病突然死亡的患者中,未发生梗死的心肌所含镁、铁和钾的浓度明显低于一组正常对照者以及一组在冠状动脉血栓形成三个多月后死亡的患者的心肌,而钙浓度则明显较高。晚期死亡组的锰和铜浓度明显低于正常组,镁浓度略有下降,这可能具有显著意义。三组之间钠浓度无显著差异。结合软水地区缺血性心脏病死亡率上升以及可能存在的矿物盐膳食缺乏情况对结果进行了讨论。

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