Westerman E L, Bradshaw M W, Williams T W
Am J Clin Pathol. 1978 May;69(5):559-60. doi: 10.1093/ajcp/69.5.559.
Agranulocytosis developed in a patient with staphylococcal osteomyelitis after 35 days of treatment with orally administered cloxacillin. The patient had fever, prostration, pharyngitis, and profound leukopenia, which subsequently abated upon withdrawal of the drug. Cloxacillin should be included in the growing list of drugs capable of producing leukopenia and agranulocytosis.
一名患有葡萄球菌骨髓炎的患者在口服氯唑西林治疗35天后发生了粒细胞缺乏症。该患者出现发热、极度虚弱、咽炎和严重白细胞减少，停药后这些症状随后缓解。氯唑西林应被列入能够导致白细胞减少和粒细胞缺乏症的药物名单之中，且这类药物的名单在不断增加。
