Chaparas S D, Maloney C J
Am Rev Respir Dis. 1978 May;117(5):897-902. doi: 10.1164/arrd.1978.117.5.897.
Homologous and heterologous skin test reactions in sensitized guinea pigs to antigens from 11 species of mycobacteria were fitted by a linear model that permitted the ranking of each species on the basis of cross reactivity. When the same species were ranked on the basis of in vitro transformation of sensitive lymphocytes in response to homologous and heterologous antigen preparations, a different ranking order was observed. Reasons for the lack of strict correlation between skin tests and in vitro lymphocyte transformations are discussed.
致敏豚鼠对11种分枝杆菌抗原的同源和异源皮肤试验反应，通过一个线性模型进行拟合，该模型允许根据交叉反应性对每个物种进行排名。当根据敏感淋巴细胞对同源和异源抗原制剂的体外转化对相同物种进行排名时，观察到了不同的排名顺序。本文讨论了皮肤试验与体外淋巴细胞转化之间缺乏严格相关性的原因。
