Kappelmann W, Hickl E J, Karius I, Stegner H E
Geburtshilfe Frauenheilkd. 1983 Jun;43 Suppl 1:30-2. doi: 10.1055/s-2008-1036589.
500 cases of carcinoma of the female breast were analysed in connection with the problem whether there is any involvement of the mamilla in this disease. The mamilla was found to be involved in 98 cases (19.6%), the incidence rate of this involved increasing with advancing age. A comparison of the types of carcinoma showed that the largest group (44%) was represented by the solid carcinomas. The percentage of carcinoma distribution was approximately the same as the share of mamilla involvement, with the exception of adenoid carcinoma. Only 12% of the mamillae were involved with a tumour diameter of less than 3 cm, whereas in the case of larger carcinomas the percentage was 30%. The distance between tumour and mamilla is also important. If the mamilla was affected, the homolateral axilla was also affected in 54% of the cases, but this figure dropped to 27% if the mamilla had remained free. This leads to the conclusion that while a conservative, non-radical surgical treatment is fundamentally possible, the selection and the formation given to the patients must be done with great care. The problem of multicentricity remains. Long-term comparisons have not been made so far.
对500例女性乳腺癌病例进行了分析，以探讨该病是否存在乳头受累问题。发现98例（19.6%）乳头受累，且这种受累的发生率随年龄增长而增加。对癌的类型进行比较显示，最大的一组（44%）为实体癌。癌的分布百分比与乳头受累比例大致相同，但腺样癌除外。肿瘤直径小于3 cm时，仅12%的乳头受累，而对于较大的癌，这一比例为30%。肿瘤与乳头之间的距离也很重要。如果乳头受累，54%的病例同侧腋窝也受累，但如果乳头未受累，这一数字降至27%。由此得出结论，虽然从根本上来说保守的、非根治性的手术治疗是可行的，但对患者的选择和告知必须非常谨慎。多中心性问题仍然存在。目前尚未进行长期比较。
