十一种抗菌剂对耐甲氧西林、耐甲氧西林和耐利福平金黄色葡萄球菌的活性。
Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus.
作者信息
Chokkavelu V, Chandrasekar P, Rolston K, LeFrock J L, Schell R F
出版信息
Chemotherapy. 1984;30(2):97-101. doi: 10.1159/000238254.
Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity against methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.
采用微量肉汤稀释技术研究了11种抗菌剂对耐甲氧西林、耐甲氧西林和耐利福平金黄色葡萄球菌的活性。香豆霉素是活性最强的药物。万古霉素、利福平、夫西地酸和N-甲酰亚胺基硫霉素对耐甲氧西林金黄色葡萄球菌（MRSA）显示出优异的活性。MRSA和耐甲氧西林及耐利福平金黄色葡萄球菌的抗菌药敏模式相似。8%的MRSA对甲氧苄啶和磺胺甲恶唑耐药。
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