• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

十一种抗菌剂对耐甲氧西林、耐甲氧西林和耐利福平金黄色葡萄球菌的活性。

Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus.

作者信息

Chokkavelu V, Chandrasekar P, Rolston K, LeFrock J L, Schell R F

出版信息

Chemotherapy. 1984;30(2):97-101. doi: 10.1159/000238254.

DOI:10.1159/000238254
PMID:6559665
Abstract

Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity against methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.

摘要

采用微量肉汤稀释技术研究了11种抗菌剂对耐甲氧西林、耐甲氧西林和耐利福平金黄色葡萄球菌的活性。香豆霉素是活性最强的药物。万古霉素、利福平、夫西地酸和N-甲酰亚胺基硫霉素对耐甲氧西林金黄色葡萄球菌(MRSA)显示出优异的活性。MRSA和耐甲氧西林及耐利福平金黄色葡萄球菌的抗菌药敏模式相似。8%的MRSA对甲氧苄啶和磺胺甲恶唑耐药。

相似文献

1
Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus.十一种抗菌剂对耐甲氧西林、耐甲氧西林和耐利福平金黄色葡萄球菌的活性。
Chemotherapy. 1984;30(2):97-101. doi: 10.1159/000238254.
2
In vitro and in vivo activity of coumermycin and other antibacterial agents against methicillin-resistant strains of Staphylococcus aureus.香豆霉素及其他抗菌剂对耐甲氧西林金黄色葡萄球菌的体外和体内活性
Chemotherapy. 1986;32(6):499-505. doi: 10.1159/000238459.
3
New trends in the chemotherapy of staphylococcal infections.葡萄球菌感染化疗的新趋势。
Chemioterapia. 1986 Apr;5(2):116-9.
4
Gentamicin- and methicillin-resistant, clinical isolates of Staphylococcus aureus: comparative in vitro and in vivo efficacy of alternative antimicrobial drugs.庆大霉素和甲氧西林耐药的金黄色葡萄球菌临床分离株:替代抗菌药物的体外和体内疗效比较
Chemotherapy. 1984;30(2):102-12. doi: 10.1159/000238255.
5
The in-vitro activity of some antimicrobial agents against methicillin-resistant Staphylococcus aureus.某些抗菌剂对耐甲氧西林金黄色葡萄球菌的体外活性。
J Antimicrob Chemother. 1985 Mar;15(3):291-5. doi: 10.1093/jac/15.3.291.
6
In vitro susceptibility of methicillin-resistant Staphylococcus aureus to imipenem and other antimicrobial agents.耐甲氧西林金黄色葡萄球菌对亚胺培南及其他抗菌药物的体外敏感性
Chemioterapia. 1987 Aug;6(4):261-3.
7
Comparative in vitro activity of coumermycin against methicillin-resistant Staphylococcus aureus.香豆霉素对耐甲氧西林金黄色葡萄球菌的体外活性比较
Antimicrob Agents Chemother. 1985 Nov;28(5):706-7. doi: 10.1128/AAC.28.5.706.
8
Methicillin- and gentamicin-resistant Staphylococcus aureus: susceptibility to fosfomycin, cefamandole, N-formimidoyl-thienamycin, clindamycin, fusidic acid and vancomycin.耐甲氧西林和庆大霉素的金黄色葡萄球菌:对磷霉素、头孢孟多、N-甲酰亚胺硫霉素、克林霉素、夫西地酸和万古霉素的敏感性
Drugs Exp Clin Res. 1985;11(1):23-7.
9
Treatment of mice infected with methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌感染小鼠的治疗
Chemotherapy. 1982;28(4):294-7. doi: 10.1159/000238093.
10
An analysis of a community-acquired pathogen in a Kentucky community: methicillin-resistant Staphylococcus aureus.肯塔基州某社区获得性病原菌分析:耐甲氧西林金黄色葡萄球菌
J Ky Med Assoc. 2005 May;103(5):206-10.

引用本文的文献

1
Recognition and clinical significance of mechanisms of bacterial resistance to beta-lactams.细菌对β-内酰胺类抗生素耐药机制的认识及其临床意义
Antonie Van Leeuwenhoek. 1984;50(5-6):711-27. doi: 10.1007/BF02386236.
2
Efficacy of penicillin G, flucloxacillin, cefazolin, fusidic acid, vancomycin, rifampicin and fosfomycin in muscular infections in mice due to Staphylococcus aureus.青霉素G、氟氯西林、头孢唑林、夫西地酸、万古霉素、利福平和磷霉素对小鼠金黄色葡萄球菌肌肉感染的疗效。
Infection. 1986 Jan-Feb;14(1):38-43. doi: 10.1007/BF01644810.
3
Vancomycin for treatment of infections with methicillin-resistant Staphylococcus aureus: are there alternatives?
万古霉素用于治疗耐甲氧西林金黄色葡萄球菌感染:是否有替代药物?
Eur J Clin Microbiol. 1986 Dec;5(6):689-92. doi: 10.1007/BF02013306.
4
Fusidic acid in infections of the external eye.夫西地酸在外眼感染中的应用
Infection. 1987 Jan-Feb;15(1):16-9. doi: 10.1007/BF01646112.
5
Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.亚胺培南/西司他丁。对其抗菌活性、药代动力学特性及治疗效果的综述。
Drugs. 1987 Mar;33(3):183-241. doi: 10.2165/00003495-198733030-00001.