Atassi M Z, Lee C L
Biochem J. 1978 May 1;171(2):429-34. doi: 10.1042/bj1710429.
The exact boundary, residue, conformational and directional definitions of the three antigenic sites of native hen's egg-white lysozyme are described. The results clearly reveal that the three antigenic sites account quantitatively for the total antigenic reactivity of the protein. Thus the entire antigenic structure of lysozyme has now been precisely determined and is briefly discussed here, together with the power of the surface-stimulation synthetic concept.
描述了天然鸡蛋清溶菌酶三个抗原位点的确切边界、残基、构象和方向定义。结果清楚地表明,这三个抗原位点在数量上占该蛋白质总抗原反应性的比例。因此,溶菌酶的整个抗原结构现已精确确定,并在此简要讨论,同时还讨论了表面刺激合成概念的作用。