巨噬细胞在体外对各种靶细胞的天然细胞毒性。II. 不同年龄大鼠的巨噬细胞。
Macrophage-mediated natural cytotoxicity against various target cells in vitro. II. Macrophages from rats of different ages.
作者信息
Keller R
出版信息
Br J Cancer. 1978 May;37(5):742-6. doi: 10.1038/bjc.1978.112.
Abstract
Adherent, predominantly phagocytic mononuclear cells from various rat tissues express spontaneous cytoxicity against diverse target cells in vitro. The extent to which cytotoxicity was expressed by effector cells depended on the age of donors. Cytolytic effector-cell capacity was already fully developed a few days after birth, and persisted over many months, but was clearly reduced in senescence. Similarly, the ability to intensify natural cytotoxicity by peptone in vivo was already fully manifested in the newborn, but was significantly diminished in old rats.
摘要
来自各种大鼠组织的贴壁、主要为吞噬性的单核细胞在体外对多种靶细胞表现出自发细胞毒性。效应细胞表现出细胞毒性的程度取决于供体的年龄。溶细胞效应细胞能力在出生后几天就已完全发育，并持续数月，但在衰老时明显降低。同样，新生大鼠体内经蛋白胨增强天然细胞毒性的能力已完全显现，但老年大鼠的这种能力则显著减弱。
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2
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