Arroyo J C, Postic B, Brown A, Harrison K, Birgenheier R, Dowda H
Am J Infect Control. 1984 Dec;12(6):329-34. doi: 10.1016/0196-6553(84)90005-1.
The failure of the 1982-1983 influenza vaccine to protect elderly NHCU residents from clinical infection with influenza A/Philippines/2/82 resulted primarily from antigenic drift of the epidemic strain, inasmuch as the attack rates in the vaccinated and nonvaccinated patients were not significantly different. This experience supports the decision to replace A/Bangkok/1/79 with A/Philippines/2/82 virus antigen in the 1983-1984 influenza vaccine.
1982 - 1983年流感疫苗未能保护老年非医院社区居民免受甲型流感/菲律宾/2/82临床感染，主要是由于流行毒株的抗原漂移，因为接种疫苗和未接种疫苗患者的发病率没有显著差异。这一经验支持了在1983 - 1984年流感疫苗中用甲型流感/菲律宾/2/82病毒抗原取代甲型流感/曼谷/1/79的决定。
