Hogan B L, Barlow D P, Kurkinen M
Ciba Found Symp. 1984;108:60-74. doi: 10.1002/9780470720899.ch5.
The major components of Reichert's membrane (laminin, type IV procollagen, entactin and heparan sulphate proteoglycan) are all synthesized by the parietal endoderm cells of the mouse embryo. Fibronectin is found mainly on the trophoblast side of Reichert's membrane and does not appear to be a major structural component. Parietal endoderm cells are thought to differentiate and migrate as individual cells from the margins of the epithelial visceral endoderm layer. They may interact with the type IV collagen in Reichert's membrane via a surface-associated protein of Mr = 47000 known as 'colligin'. Parietal endoderm cells are a rich source of mRNAs for basement membrane components and have been used to prepare a cDNA library in the expression vectors pUC8 and pUC9 from which cDNAs for type IV collagen and laminin B chains have been isolated.
赖歇特膜的主要成分（层粘连蛋白、IV型前胶原、巢蛋白和硫酸乙酰肝素蛋白聚糖）均由小鼠胚胎的壁内胚层细胞合成。纤连蛋白主要存在于赖歇特膜的滋养层一侧，似乎不是主要的结构成分。壁内胚层细胞被认为是从上皮性脏内胚层层边缘以单个细胞的形式分化和迁移的。它们可能通过一种分子量为47000的表面相关蛋白“胶原结合蛋白”与赖歇特膜中的IV型胶原相互作用。壁内胚层细胞是基底膜成分mRNA的丰富来源，并已用于在表达载体pUC8和pUC9中构建cDNA文库，从中分离出了IV型胶原和层粘连蛋白B链的cDNA。
