Genvert G, Sakauye C M, Arentsen J J
Cornea. 1984;3(4):256-61.
Thirteen eyes with sterile marginal corneal ulcers were treated with cryotherapy and conjunctival recession or resection. Ulcer progression was ultimately controlled in all cases (mean follow-up of 21 months). One eye with Mooren's ulcer required reoperation to achieve a quiescent state, and two other eyes needed conservative therapy after surgery in order to heal. The eyes required careful observation for ulcer recurrence or problems associated with the original systemic diseases, such as Sjögren's syndrome. In the majority of cases, visual acuity was not affected by the procedure. Light microscopy of the conjunctiva adjacent to the ulcer showed lymphocytes and plasma cells.
13例无菌性边缘性角膜溃疡患者接受了冷冻疗法及结膜退缩或切除术治疗。所有病例的溃疡进展最终均得到控制（平均随访21个月）。1例蚕蚀性角膜溃疡患者需要再次手术以达到静止状态，另外2只眼术后需要保守治疗才能愈合。这些眼睛需要密切观察溃疡复发情况或与原发性全身性疾病相关的问题，如干燥综合征。在大多数病例中，手术未影响视力。溃疡附近结膜的光镜检查显示有淋巴细胞和浆细胞。
