Yeragani V K, Blackman M, Baker G B
J Clin Psychiatry. 1983 Jan;44(1):27-9.
The case of a 12-year-old girl with Gilles de la Tourette's syndrome is presented, and the following factors are discussed: psychological aspects, urinary excretion of 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and unconjugated amines, and CT scan findings. The most noticeable differences from normal controls seen in the urine studies were elevated levels of beta-phenylethylamine and the catecholamine metabolites normetanephrine, MHPG, and 3-methoxytyramine, and a decrease in 5-hydroxytryptamine. A CT scan revealed a slight increase in density in the caudate nuclei bilaterally; this was thought to be due to calcification.
本文报告了一名患有 Gilles de la Tourette 综合征的 12 岁女孩的病例，并讨论了以下因素：心理方面、3-甲氧基-4-羟基苯乙二醇（MHPG）和未结合胺的尿排泄情况以及 CT 扫描结果。尿液研究中与正常对照组最显著的差异是β-苯乙胺、儿茶酚胺代谢产物去甲变肾上腺素、MHPG 和 3-甲氧基酪胺水平升高，以及 5-羟色胺减少。CT 扫描显示双侧尾状核密度略有增加；这被认为是钙化所致。
