Lundgren S, Rosenquist J B
J Oral Maxillofac Surg. 1983 Feb;41(2):99-102. doi: 10.1016/0278-2391(83)90215-x.
Recovery time, the effect of sedation or amnesia on postoperative pain, and patients' opinions of the sedation were studied. Forty operations were performed on 20 patients. Each patient had four impacted third molars removed in two sessions, one in which a new emulsion form of diazepam (Diazemuls) was used, and one in which no sedation was used. The recovery from sedation was found to be very individual and not related to the dose administered, as assessed by a simple, easy-to-use method. There was no difference in postoperative pain between the sedated and unsedated groups, and we found no correlation between postoperative pain and amnesia. Eighty-five per cent of the patients preferred sedation during surgery, even though none of them had a preoperative indication for sedation.
研究了恢复时间、镇静或遗忘对术后疼痛的影响以及患者对镇静的看法。对20名患者进行了40次手术。每位患者分两次拔除4颗阻生第三磨牙，一次使用新的地西泮乳剂（安定乳剂），另一次不使用镇静剂。通过一种简单易用的方法评估发现，镇静恢复情况因人而异，与给药剂量无关。镇静组和非镇静组术后疼痛无差异，且术后疼痛与遗忘之间无相关性。85%的患者更喜欢在手术期间接受镇静，尽管他们术前均无镇静指征。
