Platz H, Fries R, Hudec M, Min Tjoa A, Wagner R R
J Maxillofac Surg. 1983 Feb;11(1):3-12. doi: 10.1016/s0301-0503(83)80005-8.
In a retrospective study, on a sample of 1021 patients with carcinoma of the lips, oral cavity and oropharynx, the clinically available factors at the time of the patient's first admission are analysed with reference to their prognostic relevance. Prognostically relevant factors are determined by both univariate and multivariate analyses. Of the 18 factors analysed, the following seven finally proved to be prognostically relevant: tumour size, degree of infiltration, degree of histological differentiation and site by organ of the primary tumour, the combination of evidence + clinical appearance + degree of fixation of the regional lymph nodes, age of the patient, and evidence of distant metastases. On the basis of these results it will be possible to create a prognostic index. This prognostic index should be eligible for use in clinical practice, as opposed to usual classification models.
在一项回顾性研究中，对1021例唇、口腔和口咽癌患者的样本进行分析，参考患者首次入院时临床可用因素的预后相关性。通过单因素和多因素分析确定预后相关因素。在分析的18个因素中，以下7个最终被证明具有预后相关性：肿瘤大小、浸润程度、组织学分化程度、原发肿瘤的器官部位、区域淋巴结的证据+临床表现+固定程度的组合、患者年龄以及远处转移的证据。基于这些结果，有可能创建一个预后指数。与通常的分类模型不同，这个预后指数应该适用于临床实践。
