Dehò G
Virology. 1983 Apr 15;126(1):267-78. doi: 10.1016/0042-6822(83)90478-6.
A genetic map of satellite bacteriophage P4 has been constructed by means of standard multifactor crosses. The genetic map appears to be a circular permutation of the mature DNA physical map. In addition, a set of markers appear to be linked both to the left and to the right of the same gene alpha. These facts suggest that the P4 genetic map is circular. Since terminal redundancy and/or cyclic permutation are not known to be present in P4 mature DNA, the circularity of P4 genetic map may reflect the physical circularity of the molecules involved in the recombination process. The low frequency of recombination and the strong negative interference observed are in agreement with the above hypothesis.
利用标准的多因子杂交构建了卫星噬菌体P4的遗传图谱。该遗传图谱似乎是成熟DNA物理图谱的环状排列。此外，一组标记似乎与同一基因α的左侧和右侧都相连。这些事实表明P4遗传图谱是环状的。由于未知P4成熟DNA中存在末端冗余和/或环状排列，P4遗传图谱的环状性可能反映了重组过程中所涉及分子的物理环状性。观察到的低重组频率和强负干扰与上述假设一致。
