Correlation between MAO activity in blood platelets obtained by single and multiple centrifugations.

Monoamine oxidase (MAO) activity in human blood platelets isolated by a single centrifugation at 600g for 2 1/2 minutes, which isolates only 45-65% of total platelets, was highly correlated with the MAO activity in platelets isolated by a method which isolates essentially 100% of platelets (r = 0.95, p less than 0.01). These results indicate that the single centrifugation method, which isolates only a portion of platelets, gives a reliable estimate of MAO activity in the entire platelet population.