Scott M L, Golden C J, Ruedrich S L, Bishop R J
Psychiatry Res. 1983 Feb;8(2):91-3. doi: 10.1016/0165-1781(83)90095-1.
Major depression accompanied by psychosis may be a separate nosological entity from nonpsychotic depression. Investigators have noted behavioral and biochemical differences in psychotic and nonpsychotic patients, as well as differences in response to treatment. A previous study using computed tomography (CT) found enlargement of the lateral cerebral ventricles in patients with manic-depressive illness with psychotic symptoms. The present study examined CT scans of patients with major affective illness that was accompanied by hallucinations, delusions, or both. The ventricles of the depressed group were significantly larger than those of a group of normal controls.
伴有精神病性症状的重度抑郁症可能是一种与非精神病性抑郁症不同的疾病实体。研究人员已经注意到精神病性患者和非精神病性患者在行为和生化方面的差异，以及对治疗反应的差异。先前一项使用计算机断层扫描（CT）的研究发现，有精神病性症状的躁郁症患者侧脑室扩大。本研究检查了伴有幻觉、妄想或两者皆有的重度情感性疾病患者的CT扫描结果。抑郁组的脑室明显大于一组正常对照组。
