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[急性白血病中引发Sweet综合征的病变:发生于治疗性再生障碍阶段]

[Lesions evoking Sweet's syndrome in acute leukemia: occurring during the stage of therapeutic aplasia].

作者信息

Milpied N, Harousseau J L, Castaigne S, Bureau B, Reynaud C, Rodat O

出版信息

Ann Med Interne (Paris). 1983;134(1):38-41.

PMID:6574722
Abstract

Acute febrile neutrophilic dermatosis, so called Sweet's Syndrome is a distinct dermatological disease defined by constant clinical and histological features: Eruption of painful, tender, raised erythematous plaques of face and neck with fever. Dense dermal infiltration with mature neutrophil polymorphs. Sweet's Syndrome may occur during the course of chronic or acute haematological diseases such as chronic myelogenous leukemia or acute non lymphoblastic leukemia. In all cases, the counts of Neutrophil Polymorphs were normal or above normal limits. We report a case of Sweet's Syndrome occurring during the aplastic period induced by the treatment of an acute myelo monocytic leukemia, and discuss the responsibility of white blood cells transfusion in genesis of typical histological aspect.

摘要

急性发热性嗜中性皮病,即所谓的斯威特综合征,是一种具有独特临床和组织学特征的皮肤病:面部和颈部出现疼痛、触痛、隆起的红斑性斑块并伴有发热。真皮内有成熟中性多形核白细胞密集浸润。斯威特综合征可能发生在慢性或急性血液系统疾病过程中,如慢性粒细胞白血病或急性非淋巴细胞白血病。在所有病例中,中性多形核白细胞计数正常或高于正常范围。我们报告一例在急性粒单核细胞白血病治疗诱导的再生障碍期发生的斯威特综合征病例,并讨论白细胞输血在典型组织学表现发生中的作用。

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