Dupuis A, Michaud J, Diner P, Toty L, Personne C
Rev Stomatol Chir Maxillofac. 1983;84(3):154-6.
Ameloblastoma is a locally invasive, histologically nonmalignant tumor that may on very rare occasions give rise to metastases. A patient with a mandibular ameloblastoma presenting typical histologic appearances developed a pulmonary metastasis confirmed by histology as arising from the primary tumor. Two groups of these extremely rare malignant ameloblastomas can be distinguished: those without histologic signs of degeneration that give rise to metastases identical to the primary lesion, and those with degenerative signs provoking metastases with the histologic appearance of undifferentiated carcinoma. No relation appears to exist between size of primary tumor, histologic type of ameloblastoma, or its course and tendency to produce metastases.
成釉细胞瘤是一种局部侵袭性、组织学上为非恶性的肿瘤，极少数情况下可能发生转移。一名患有下颌成釉细胞瘤且呈现典型组织学表现的患者发生了肺转移，经组织学证实为源自原发肿瘤。可区分出两组这类极其罕见的恶性成釉细胞瘤：一组没有退变的组织学征象，发生的转移灶与原发病变相同；另一组有退变征象，引发的转移灶具有未分化癌的组织学表现。原发肿瘤的大小、成釉细胞瘤的组织学类型或其病程与发生转移的倾向之间似乎没有关联。
