妊娠子宫引流淋巴结中淋巴细胞积聚和增殖的变化。
Changes in lymphocyte accumulation and proliferation in the lymph nodes draining the pregnant uterus.
作者信息
Ansell J D, McDougall C M, Speedy G, Inchley C J
出版信息
Clin Exp Immunol. 1978 Mar;31(3):397-407.
Abstract
Changes in weight, lymphocyte accumulation and cellular proliferation have been measured in the lymph nodes draining the uterus during inter- and intra-strain pregnancies and compared with similar effects after other antigenic stimuli. From the data obtained it was concluded that "paternal" antigenic stimulation from the conceptus initiated an immune response in these nodes. The mechanisms of the subsequent suppression of this response are discussed.
摘要
在不同品系间和品系内妊娠期间，对子宫引流淋巴结的重量变化、淋巴细胞聚集和细胞增殖进行了测量，并与其他抗原刺激后的类似效应进行了比较。根据所获得的数据得出结论，来自胚胎的“父系”抗原刺激在这些淋巴结中引发了免疫反应。随后讨论了这种反应被抑制的机制。
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本文引用的文献
1
IMMUNE RESPONSE ENGENDERED IN MICE BY MULTIPARITY.
Transplantation. 1964 May;2:416-25. doi: 10.1097/00007890-196405000-00011.
2
PREGNANCY INDUCED HEMAGGLUTININS TO PATERNAL H-2 ANTIGENS IN MULTIPAROUS MICE.
Transplantation. 1964 May;2:357-61. doi: 10.1097/00007890-196405000-00004.
3
Studies of the primary and the secondary immune responses of lymph nodes draining homografts of fresh cancellous bone (with particular reference to mechanisms of lymph node reactivity).
Ann N Y Acad Sci. 1962 Oct 24;99:821-60. doi: 10.1111/j.1749-6632.1962.tb45365.x.
4
Experimental study of the behavior of adult human skin homografts during pregnancy. A preliminary report.
Am J Obstet Gynecol. 1962 Oct 15;84:1096-103. doi: 10.1016/0002-9378(62)90560-4.
5
6
Cellular changes in lymph nodes and spleen following skin homografting in the rabbit.
J Anat. 1955 Jul;89(3):283-92.
7
An attempt to detect M-2 antigens on mouse eggs.
Transplantation. 1968 May;6(3):478-9. doi: 10.1097/00007890-196805000-00020.
8
The morphological identity of maternal cells in newborn mice.
Blood. 1970 Oct;36(4):480-9.
9
Immune responses in congenitally thymus-less mice. I. Absence of response to oxazolone.
Clin Exp Immunol. 1972 Jan;10(1):151-61.
10
Fetal erythrocytes in maternal circulation of 155 Rh-negative women.
Obstet Gynecol. 1969 Aug;34(2):143-50.
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