Jackson R P
Clin Orthop Relat Res. 1978 Mar-Apr(131):229-33.
A review of 3 new osteoblastomas and 181 previously reported osteoblastomas revealed 18 recurrences (9.8% recurrence rate). Recurrence was more common in the spine and pelvis. Recurrences were reported as late as 9 years after excision of osteoblastomas and long-term follow-up is indicated in this lesion. Five recurrences were reported to undergo apparent sarcomatous change. Complete en bloc resection is the preferred treatment of osteoblastomas. No recurrence has ever been reported after complete resection, however, apparent incomplete excision has given cures in many cases. Radiotherapy does not appear to prevent recurrence. Its immediate postoperative use is not recommended and may possibly be associated with apparent late sarcomatous change in some cases. Since the efficacy of radiotherapy in the treatment of established recurrence still remains obscure, further surgical intervention is indicated.
对3例新发骨母细胞瘤和181例既往报道的骨母细胞瘤进行回顾性研究发现,有18例复发(复发率为9.8%)。复发在脊柱和骨盆更为常见。骨母细胞瘤切除术后9年仍有复发报道,因此该病变需要长期随访。据报道,5例复发发生了明显的肉瘤样变。整块完整切除是骨母细胞瘤的首选治疗方法。完整切除后从未有过复发报道,然而,在许多病例中,明显的不完全切除也实现了治愈。放疗似乎不能预防复发。不建议术后立即使用放疗,在某些情况下,放疗可能与明显的晚期肉瘤样变有关。由于放疗对已确诊复发的治疗效果仍不明确,因此需要进一步的手术干预。