Niebrugge D J, Benjamin D R
Cancer. 1983 Dec 1;52(11):2162-4. doi: 10.1002/1097-0142(19831201)52:11<2162::aid-cncr2820521131>3.0.co;2-a.
Two patients who presented with bone marrow necrosis and eventually developed acute lymphocytic leukemia are reported, and similar cases in the literature are reviewed. Both patients responded to chemotherapy. Several possible mechanisms are discussed. Bone marrow necrosis appears to be another condition preceding acute lymphocytic leukemia in children.
报道了两名出现骨髓坏死并最终发展为急性淋巴细胞白血病的患者，并对文献中的类似病例进行了回顾。两名患者对化疗均有反应。讨论了几种可能的机制。骨髓坏死似乎是儿童急性淋巴细胞白血病之前出现的另一种病症。
