Burden H W, Lawrence I E, Louis T M, Hodson C A
Neuroendocrinology. 1983 Oct;37(4):288-90. doi: 10.1159/000123561.
Rats were vagotomized at proestrus and 4 days later serum prolactin and progesterone were determined by radioimmunoassay. The histology of the ovaries and the activity of ovarian delta 5-3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) were also studied. There was no difference between hormone values in sham and vagotomized rats 4 days after surgery. In addition, the ovarian histology and activity of 3 beta-HSD were similar in both sham and vagotomized animals. We conclude that vagotomy at proestrus does not interrupt estrous cycles by activating the corpus luteum.
在动情前期对大鼠进行迷走神经切断术，4天后通过放射免疫分析法测定血清催乳素和孕酮水平。同时还研究了卵巢的组织学以及卵巢δ5-3β-羟基类固醇脱氢酶（3β-HSD）的活性。术后4天，假手术组和迷走神经切断组大鼠的激素水平没有差异。此外，假手术组和迷走神经切断组动物的卵巢组织学和3β-HSD活性相似。我们得出结论，动情前期进行迷走神经切断术不会通过激活黄体来干扰发情周期。
