Gilmore O J, Rosin R D, Exarchakos G, Ellis H
Eur Surg Res. 1978;10(2):94-104. doi: 10.1159/000127996.
The effect of povidone-iodine (0.1% available iodine) irrigation on colonic anastomosis healing was investigated in 196 Sprague-Dawley rats. Each end of the divided colon was irrigated with 5 ml of povidone-iodine solution or with an equal volume of normal saline before anastomosis and again after the anastomosis had been completed. Healing was assessed at 2, 4, 6, 8, 10, and 14 days after operation: macroscopically, mechanically, histologically and angiigraphically. Povidone-iodine irrigation did not impair healing in any way.
在196只斯普拉格-道利大鼠中研究了聚维酮碘（有效碘含量为0.1%）冲洗对结肠吻合口愈合的影响。在吻合术前，将5毫升聚维酮碘溶液或等体积的生理盐水冲洗至切断结肠的两端，在吻合完成后再次冲洗。在术后2、4、6、8、10和14天评估愈合情况：通过宏观、力学、组织学和血管造影进行评估。聚维酮碘冲洗并未以任何方式损害愈合。
