Matouschek E, Huber R, Schneider J, Vogg H
Eur Urol. 1978;4(3):206-11. doi: 10.1159/000473951.
Concentration and excretion in 24-hour urine, as well as serum concentrations of Na, K, Mg, Ca, Cl, P, uric acid and citrate were investigated in 209 calcium oxalate stone patients and 42 stone-free patients. Especially the concentration values of the urine components, except for uric acid and citrate, were found to be significantly lower for calcium oxalate stone patients. 21% of the stone patients showed hypercalciuria; hypercalciuria combined with hyperuricuria was found in only 7.1% of the cases and a solitary hyperuricuria in only 17%. As for kidney cortex, kidney papilla and muscle tissue in 10 calcium oxalate stone patients and 10 stone-free patients, the concentrations of Na, K, Ca, Mg as well as some trace elements were determined quantitatively by means of neutron activation analysis. Statistic analysis yielded a significantly lower sodium content of the kidney cortex within the stone-carrying group. Mean values of the calcium concentration in stone patients were lower for papilla and muscle tissue than in the control group. For magnesium no clear differences were found. The iron content in the papilla and muslce tissue of stone patients was significantly lower.
对209例草酸钙结石患者和42例无结石患者的24小时尿液中的浓度和排泄情况以及血清中钠、钾、镁、钙、氯、磷、尿酸和柠檬酸盐的浓度进行了研究。结果发现，除尿酸和柠檬酸盐外，草酸钙结石患者尿液成分的浓度值显著较低。21%的结石患者出现高钙尿症；仅7.1%的病例中发现高钙尿症合并高尿酸尿症，仅17%的病例中发现单纯高尿酸尿症。对10例草酸钙结石患者和10例无结石患者的肾皮质、肾乳头和肌肉组织，采用中子活化分析法对钠、钾、钙、镁以及一些微量元素的浓度进行了定量测定。统计分析结果显示，结石组肾皮质中的钠含量显著较低。结石患者乳头和肌肉组织中钙浓度的平均值低于对照组。镁含量未发现明显差异。结石患者乳头和肌肉组织中的铁含量显著较低。
