Kondo T, Magee D F
Experientia. 1978 May 15;34(5):607. doi: 10.1007/BF01936986.
Isoproterenol if given during methacholine stimulation in dogs neither depresses gastric secretion nor elevates serum gastrin. Therefore, we conclude that beta adrenergics (isoproterenol) are unlikely to be direct liberators of gastrin, but raise serum gastrin indirectly only if they inhibit gastric secretion.
在犬的乙酰甲胆碱刺激过程中给予异丙肾上腺素,既不会抑制胃酸分泌,也不会升高血清胃泌素。因此,我们得出结论,β肾上腺素能药物(异丙肾上腺素)不太可能是胃泌素的直接释放剂,只有在抑制胃酸分泌时才会间接升高血清胃泌素。