Cline M J
Mol Cell Biochem. 1984;59(1-2):3-10. doi: 10.1007/BF00231302.
A number of techniques are available for insertion of new genetic information into mammalian cells. some of these have been used successfully for genetic modification of germ line cells and somatic cells of living animals. Some of these techniques may be applicable to treatment of some of the genetic diseases of man, once problems related to the control of expression of introduced genes are solved.
有多种技术可用于将新的遗传信息插入哺乳动物细胞。其中一些技术已成功用于对活体动物的生殖系细胞和体细胞进行基因改造。一旦与引入基因的表达控制相关的问题得到解决,其中一些技术可能适用于治疗人类的某些遗传疾病。