机械电换能器在鸡前庭毛细胞中具有离散电导。
Mechanoelectrical transducer has discrete conductances in the chick vestibular hair cell.
作者信息
Ohmori H
出版信息
Proc Natl Acad Sci U S A. 1984 Mar;81(6):1888-91. doi: 10.1073/pnas.81.6.1888.
Abstract
Properties of mechanoelectrical transduction were studied at the single-cell level by applying a whole-cell recording variation of the patch-clamp technique to dissociated vestibular hair cells of chicks. The hair bundle was directly stimulated by a glass rod, and transduction currents were recorded from the cell body. After a triangular movement of the stimulating probe, the transduction current was generated stepwise between discrete levels of amplitude. The minimum step amplitude was -1.8 pA at -27 mV in Na-containing normal saline.
摘要
通过将膜片钳技术的全细胞记录变体应用于雏鸡分离的前庭毛细胞，在单细胞水平上研究了机械电转导的特性。用玻璃棒直接刺激毛束，并从细胞体记录转导电流。在刺激探针进行三角运动后，转导电流在离散的幅度水平之间逐步产生。在含钠的生理盐水中，-27 mV时的最小步幅为-1.8 pA。
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