Botts J, Takashi R, Torgerson P, Hozumi T, Muhlrad A, Mornet D, Morales M F
Proc Natl Acad Sci U S A. 1984 Apr;81(7):2060-4. doi: 10.1073/pnas.81.7.2060.
It is proposed that the myosin subfragment 1 moiety of the muscle contractile apparatus is a self-contained "engine" whose operational plan is based on the interactive nature of ATP (or degradation intermediate) binding and actin binding, made possible by an intersite communication system. It is suggested that the spatial information required for examining this engine can, at least provisionally, be derived from fluorescence resonance energy transfer measurements interpreted by the Förster equation and that the existence of an intersite communication system can be deduced from piece-wise detection of interacting pairs of points.
有人提出，肌肉收缩装置的肌球蛋白亚片段1部分是一个独立的“引擎”，其运作方案基于ATP（或降解中间体）结合与肌动蛋白结合的相互作用性质，这是由位点间通信系统实现的。有人认为，用于研究这个“引擎”所需的空间信息至少在暂时情况下，可以从由Förster方程解释的荧光共振能量转移测量中获得，并且位点间通信系统的存在可以从相互作用点对的逐段检测中推导出来。
