从化学转化的人细胞系中克隆一个新的转化基因
Molecular cloning of a new transforming gene from a chemically transformed human cell line.
作者信息
Cooper C S, Park M, Blair D G, Tainsky M A, Huebner K, Croce C M, Vande Woude G F
出版信息
Nature. 1984;311(5981):29-33. doi: 10.1038/311029a0.
DOI:10.1038/311029a0
PMID:6590967
Abstract
Molecular cloning of the transforming gene from a chemically transformed human osteosarcoma-derived cell line enables the gene to be mapped to chromosome 7 (7p11.4-7qter) and by this criterion and by direct hybridization to be shown to be unrelated to known oncogenes.
摘要
从化学转化的人骨肉瘤衍生细胞系中克隆转化基因，可将该基因定位到7号染色体（7p11.4 - 7qter），根据这一标准并通过直接杂交表明其与已知癌基因无关。
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