有和没有精神分裂症家族史的患者中的人类白细胞抗原（HLA）抗原
HLA antigens in patients with and without a family history of schizophrenia.
作者信息
Rudduck C, Franzén G, Löw B, Rorsman B
出版信息
Hum Hered. 1984;34(5):291-6. doi: 10.1159/000153482.
PMID:6592138
Abstract
Frequencies of HLA antigens (A, B, C and DR) were studied in patients with (n = 49) and without (n = 67) a family history of schizophrenia and in controls. Among the patients with a family history of schizophrenia significant increases were found in the A3 and B5 antigens while significant decreases were observed for the A1, A11 and B8 antigens. In a material of schizophrenic siblings the sharing of HLA haplotypes was consistent with normal segregation.
摘要
对有精神分裂症家族史（n = 49）和无精神分裂症家族史（n = 67）的患者以及对照组进行了HLA抗原（A、B、C和DR）频率研究。在有精神分裂症家族史的患者中，发现A3和B5抗原显著增加，而A1、A11和B8抗原显著减少。在一组精神分裂症患者同胞样本中，HLA单倍型的共享与正常分离一致。
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