Pola P, Tondi P, Flore R, Serricchio M, Dal Lago A, Amanti C, Consorti F, Benedetti M, Midiri H
Int J Clin Pharmacol Res. 1983;3(3):179-84.
Ten surgical patients--4 males and 6 females, mean age: 46.7 years--affected by various pathological conditions were selected for this clinical trial. The patients were divided into two groups of 5 as follows: Group I on the third day received 10%. Intralipid (500 mg) + l-carnitine i.v. (100 mg/kg); on the sixth day 10% Intralipid (500 mg) infusion was given alone. Group II on the third day received 10% Intralipid (500 mg) infusion, and on the sixth day 10% Intralipid (500 mg) + l-carnitine (100 mg/kg). The laboratory parameters (cholesterol, triglycerides, HDL, LDL, VLDL, apolipoprotein A and B) showed that the lipids administered with l-carnitine were more rapidly metabolized than those without.
十名患有各种病理状况的外科手术患者（4名男性和6名女性，平均年龄：46.7岁）被选入该临床试验。患者被分为两组，每组5人，如下所示：第一组在第三天接受10%英脱利匹特（500毫克）+左旋肉碱静脉注射（100毫克/千克）；在第六天单独给予10%英脱利匹特（500毫克）输注。第二组在第三天接受10%英脱利匹特（500毫克）输注，在第六天接受10%英脱利匹特（500毫克）+左旋肉碱（100毫克/千克）。实验室参数（胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白、载脂蛋白A和B）显示，与左旋肉碱一起给予的脂质比未与左旋肉碱一起给予的脂质代谢更快。
