Greenwald P, Kovasznay B, Collins D N, Therriault G
J Natl Cancer Inst. 1984 Nov;73(5):1107-9.
Vietnam service and military service experiences of 281 men with sarcomas of soft tissues were compared in this epidemiologic study to a control group of men derived from driver's license files and matched on 5-year period of birth and ZIP code of residence. No direct association was found for service in Vietnam (odds ratio, 0.53; confidence limits, 0.21-1.31) or for any military service (odds ratio, 0.53; confidence limits, 0.37-0.76). A multivariate matched logistic regression analysis showed similar results for Vietnam service while controlling for military service. Results also were similar when the 130 cases who had died were compared to a second control group derived from death certificates. Finally, no significant associations were found for "Agent Orange" or other variables that might be related to herbicide exposure.
在这项流行病学研究中,将281名患有软组织肉瘤的男性的越南服役经历和军事服役经历,与一组从驾照档案中选取的男性对照组进行了比较,该对照组在出生年份和居住邮编方面进行了匹配。未发现越南服役(优势比为0.53;置信区间为0.21 - 1.31)或任何军事服役(优势比为0.53;置信区间为0.37 - 0.76)存在直接关联。多变量匹配逻辑回归分析在控制军事服役因素的情况下,得出了与越南服役情况相似的结果。当将130名已死亡的病例与从死亡证明中选取的第二个对照组进行比较时,结果也相似。最后,未发现与“橙剂”或其他可能与除草剂接触相关的变量存在显著关联。