Moen M, Bratlie A, Moen T
Acta Obstet Gynecol Scand Suppl. 1984;123:25-7. doi: 10.3109/00016348409156977.
Previous studies have demonstrated a hereditary tendency to develop endometriosis and the incidence of the disease varies in different ethnic groups. The genetic background to these differences has not been clearly explained. The present investigation was performed to seek a possible association between certain HLA antigens and endometriosis. One hundred patients were typed for HLA-A, -B and -C, and of these 24 were also typed for HLA-DR. No significant deviations from the antigen frequencies in a normal population were found. We conclude that the development of endometriosis does not seem to be associated with HLA-A, -B, -C or -DR antigens.
先前的研究已经证明子宫内膜异位症具有遗传倾向，并且该疾病的发病率在不同种族群体中有所不同。这些差异的遗传背景尚未得到明确解释。本研究旨在探寻某些人类白细胞抗原（HLA）与子宫内膜异位症之间可能存在的关联。对100名患者进行了HLA - A、- B和 - C分型，其中24名患者还进行了HLA - DR分型。未发现与正常人群抗原频率有显著偏差。我们得出结论，子宫内膜异位症的发生似乎与HLA - A、- B、- C或 - DR抗原无关。
