Hirschfeld Z, Friedman M, Golomb G, Ben-Yaacov D
J Oral Rehabil. 1984 Sep;11(5):477-82. doi: 10.1111/j.1365-2842.1984.tb00600.x.
The aim of this work was to test the effectiveness of a local sustained release application of chlorhexidine in prevention of plaque formation in a group of five partial denture wearers when oral hygiene procedures were withdrawn. The clinical study demonstrates that coating of the partial dentures with ethyl cellulose polymer containing the drug, prevents accumulation of plaque during a period of 12 days. No typical side effects of chlorhexidine such as tooth staining and unpleasant taste were observed during the study.
这项工作的目的是测试在停止口腔卫生措施时，对一组五名局部义齿佩戴者局部持续释放洗必泰在预防牙菌斑形成方面的有效性。临床研究表明，用含有该药物的乙基纤维素聚合物涂覆局部义齿，可在12天内防止牙菌斑积聚。在研究期间未观察到洗必泰的典型副作用，如牙齿染色和异味。
