Juchmès J, Bourdon V
Arch Int Physiol Biochim. 1976 Oct;84(4):801-5. doi: 10.3109/13813457609067055.
The urinary clearance for DL-[3H] noradrenaline has been measured in four human subjects. The mean ratio of noradrenaline clearance over glomerular filtration rate was 0.93, the confidence limit for the mean at the 5% level being 0.81-1.06. These results are in perfect agreement with those obtained in dogs with the same experimental procedure. It is concluded that the urinary excretion of noradrenaline is strictly proportional to the glomerular filtration rate.
已在四名人类受试者中测量了DL-[3H]去甲肾上腺素的尿清除率。去甲肾上腺素清除率与肾小球滤过率的平均比值为0.93,5%水平下平均值的置信区间为0.81-1.06。这些结果与采用相同实验程序在犬类中获得的结果完全一致。结论是,去甲肾上腺素的尿排泄与肾小球滤过率严格成正比。