Eur J Respir Dis Suppl. 1984;132:1-137.
The lung function of 11,497 Sydney schoolchildren was measured at regular intervals over a ten year period. The prevalences of respiratory illness in infancy and childhood and cigarette smoking in teenage years were documented and the effects on lung function assessed. Using maximal expiratory flow at 50% of forced vital capacity (V 50), small but persisting changes in lung function were found in both males and females who had had bronchitis and/or asthma before the age of 2 years. Subsequent bronchitis had an additional effect on lung function in these children with early respiratory illness. Subsequent asthma had the greatest effect on lung function and the deficit increased as these children approached adult life. Deficits in lung function attributable to smoking were found in some children by the age of 14 years and occurred in children with previously normal lung function. Smoking in children who had a history of asthma was associated with severe abnormalities of lung function.
在十年期间，对11497名悉尼学童的肺功能进行了定期测量。记录了婴儿期和儿童期呼吸系统疾病的患病率以及青少年时期的吸烟情况，并评估了其对肺功能的影响。使用用力肺活量50%时的最大呼气流量（V50），发现2岁前患过支气管炎和/或哮喘的男性和女性的肺功能均出现了虽小但持续的变化。随后的支气管炎对这些患有早期呼吸系统疾病的儿童的肺功能有额外影响。随后的哮喘对肺功能影响最大，随着这些儿童接近成年，肺功能缺损增加。到14岁时，在一些儿童中发现了因吸烟导致的肺功能缺损，且发生在之前肺功能正常的儿童中。有哮喘病史的儿童吸烟与严重的肺功能异常有关。
