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一种多位点连续时间选择模型。

A multi-locus continuous-time selection model.

作者信息

Moody M

出版信息

J Math Biol. 1978 Mar 28;5(3):281-91. doi: 10.1007/BF00276123.

Abstract

A continuous time selection model is formulated for a diploid monoecious population with multiple alleles at each of an arbitrary number of loci, incorporating differential fertility and mortality as well as arbitrary mating and age structure. The model is simplified in the case of age-independence and for the case of a stable age distribution. The age-independent model is examined in detail for the special case of multiple alleles at each of two loci. This model is analyzed under the assumptions of random mating and additive fertilities, with close attention given to the behavior of the system with respect to Hardy-Weinberg proportions and linkage equilibrium.

摘要

针对一个二倍体雌雄同株种群构建了一个连续时间选择模型,该种群在任意数量的基因座上各有多个等位基因,纳入了不同的生育率和死亡率以及任意的交配和年龄结构。在年龄无关的情况下以及稳定年龄分布的情况下对该模型进行了简化。针对两个基因座上各有多个等位基因的特殊情况,详细研究了年龄无关模型。在随机交配和加性生育率的假设下对该模型进行了分析,并密切关注该系统在哈迪 - 温伯格比例和连锁平衡方面的行为。

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