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实验性脊髓损伤的组织病理学。全身血压的影响。

The histopathology of experimental spinal cord trauma. The effect of systemic blood pressure.

作者信息

Rawe S E, Lee W A, Perot P L

出版信息

J Neurosurg. 1978 Jun;48(6):1002-7. doi: 10.3171/jns.1978.48.6.1002.

DOI:10.3171/jns.1978.48.6.1002
PMID:660233
Abstract

The early sequential histopathological alterations following a concussive paraplegic injury to the posterior thoracic spinal cord in cats were studied. The lack of significant progression of hemorrhages over a 4-hour period after injury indicates that most hemorrhages probably occur within the first hour. The marked enhancement or retardation of hemorrhages in the post-injury period, when the blood pressure was increased or decreased, respectively, demonstrates the loss of autoregulation of spinal cord vasculature at the trauma site after a concussive paraplegic injury. Progressive edema formation was evident over a 4-hour period following injury, and it could be enhanced or retarded by elevation or reduction of the systemic blood pressure.

摘要

研究了猫胸段脊髓后部震荡性截瘫损伤后的早期连续组织病理学改变。损伤后4小时内出血无明显进展,表明大多数出血可能发生在最初1小时内。分别在血压升高或降低的损伤后时期,出血明显增强或延迟,这表明震荡性截瘫损伤后创伤部位脊髓血管系统的自动调节功能丧失。损伤后4小时内逐渐形成明显的水肿,全身血压升高或降低可增强或抑制水肿。

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1
The histopathology of experimental spinal cord trauma. The effect of systemic blood pressure.实验性脊髓损伤的组织病理学。全身血压的影响。
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