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Peripheral lymphocyte response to PHA and T cell population among atomic bomb survivors.

作者信息

Akiyama M, Yamakido M, Kobuke K, Dock D S, Hamilton H B, Awa A A, Kato H

出版信息

Radiat Res. 1983 Mar;93(3):572-80.

PMID:6602350
Abstract

The percentage of T lymphocytes of atomic bomb survivors showed no change as a function of age or exposure dose. The percentage of T cells was slightly lower in malignant-tumor patients than in the control group, but was significantly higher in the group with chromosomal aberrations than in the control group. The percentages of phytohemagglutinin (PHA)-induced transformation of peripheral lymphocytes decreased significantly with age in the 0 rad control group and the 200+ rad exposure group, particularly so in the latter. The malignant-tumor group also showed lower percentages of PHA-induced transformation than the control group. The percentages of PHA-induced transformation of lymphocytes of the chromosomal-aberration group were significantly depressed as compared with that of the control group.

摘要

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