Jenkins C D, Stanton B A, Savageau J A, Denlinger P, Klein M D
JAMA. 1983 Aug 12;250(6):782-8. doi: 10.1001/jama.250.6.782.
To evaluate the benefits of coronary artery bypass graft (CABG) surgery, we interviewed and tested 318 patients (268 men and 50 women) younger than age 70 before and six months after elective CABG at four university medical centers. Biomedical, psychoneurological, physical function, role function, occupational, social, family, sexual, emotional, and attitudinal variables were assessed. Quantitative comparisons showed improvement on many factors. Angina was completely relieved for 69% to 85% of persons, depending on whether it had been induced by exertion or other events. Disability days were reduced more than 80%. Seventy-five percent of employed persons had returned to work. Anxiety, depression, fatigue, and sleep problems declined. Vigor and well-being scores rose significantly. When losses were expected (eg, psychoneurological function, marital adjustment), they generally were not found. For none of the more than 60 outcome variables was widespread serious worsening found. The findings suggest that the great majority of patients are able to resume normal economic and social functioning within six months after CABG.
为评估冠状动脉搭桥术(CABG)的益处,我们在四家大学医学中心对318例年龄小于70岁的患者(268名男性和50名女性)在择期冠状动脉搭桥术前及术后6个月进行了访谈和测试。评估了生物医学、心理神经学、身体功能、角色功能、职业、社会、家庭、性、情感和态度等变量。定量比较显示许多因素都有改善。根据心绞痛是由运动还是其他事件诱发,69%至85%的患者心绞痛完全缓解。残疾天数减少了80%以上。75%的就业人员已重返工作岗位。焦虑、抑郁、疲劳和睡眠问题有所减少。活力和幸福感得分显著提高。当预期会有损失时(如心理神经功能、婚姻适应),通常并未发现。在60多个结局变量中,均未发现普遍的严重恶化情况。研究结果表明,绝大多数患者在冠状动脉搭桥术后6个月内能够恢复正常的经济和社会功能。