Passive transfer of immunity against hepatic amoebiasis in the hamster by cells.

The role of passive cell-mediated transfer of immunity in hepatic amoebiasis in hamsters was studied. The transfer of peritoneal cells from hamsters vaccinated against or protected from hepatic amoebiasis and from those with hepatic amoebiasis, as well as of spleen cells from vaccinated or protected, but not from infected hamsters, conferred immunity against hepatic amoebiasis in recipient normal hamsters. Treatment of the spleen cells from protected hamsters with anti T-cell serum abolished their ability to transfer immunity. It appears that the effector mechanism in this system is T-cell dependent.