Peyriéras N, Hyafil F, Louvard D, Ploegh H L, Jacob F
Proc Natl Acad Sci U S A. 1983 Oct;80(20):6274-7. doi: 10.1073/pnas.80.20.6274.
A monoclonal antibody has allowed the characterization of various forms of uvomorulin, a glycoprotein involved in the process of compaction of mouse morula. In addition to various degradation products, uvomorulin exists as a 120-kilodalton exocellular molecule stable at the cell surface. A short-lived 135-kilodalton precursor of uvomorulin has been detected after 10-min pulse labeling. Uvomorulin-like molecules are found on various tissues at various stages of development of the mouse.
一种单克隆抗体已使人们能够对多种形式的尿膜素进行表征，尿膜素是一种参与小鼠桑椹胚致密化过程的糖蛋白。除了各种降解产物外，尿膜素以一种120千道尔顿的细胞外分子形式存在，在细胞表面稳定。在进行10分钟的脉冲标记后，已检测到尿膜素的一种半衰期较短的135千道尔顿前体。在小鼠发育的各个阶段，在各种组织上都发现了类似尿膜素的分子。
