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使用欧洲经济区吻合器控制食管静脉曲张出血。

Use of the EEA stapling instrument for control of bleeding esophageal varices.

作者信息

Wanamaker S R, Cooperman M, Carey L C

出版信息

Surgery. 1983 Oct;94(4):620-6.

PMID:6604952
Abstract

Transection of the esophagus with the EEA stapling device (United States Surgical Corp.) has been used to treat 20 patients with bleeding esophageal varices. Their ages ranged from 38 to 73 years (mean 56.7 years). Sixteen patients (80%) had Laënnec's cirrhosis. A previous occluded portosystemic shunt was present in five patients. Based on Child's classification, there were one class A patient, 18 class C patient, and one patient who was unclassified. Five patients underwent elective operation; four survived (80%). The cases of the remaining 15 patients were treated as emergencies or semiemergencies after intensive preoperative intervention including intravenous administration of vasopressin (Pitressin) (100%), balloon tamponade in 11 (73%), and sclerotherapy in three (20%) failed to control the hemorrhage adequately. None of the patients had rebleeding from varices during the postoperative period. However, 11 of the 15 patients (73%) died. All deaths were related to liver failure, except for two patients who died of irreversible acidosis secondary to shock. Technical difficulty was encountered six times with use of the stapling device, resulting in three perforations of the esophagus, which were recognized and repaired at the time. No deaths were attributed to this complication. Of the eight patients who survived the early postoperative period, three have since died--two of variceal hemorrhage and the other of hepatic failure. Two others have had recurrent variceal hemorrhage controlled by sclerotherapy. The duration of follow-up ranges from 10 to 60 months (mean 31 months). Transection of the esophagus with the EEA stapling device for acute variceal hemorrhage is associated with an excessively high mortality rate despite the fact that it controls variceal hemorrhage. It appears to be of value when used on an elective basis for selected patients who cannot benefit from other modes of treatment.

摘要

采用美国外科公司生产的EEA吻合器横断食管治疗20例食管静脉曲张出血患者。患者年龄38至73岁(平均56.7岁)。16例(80%)有Laënnec肝硬化。5例曾行闭塞的门体分流术。根据Child分级,A级1例,C级18例,1例未分级。5例行择期手术,4例存活(80%)。其余15例患者经强化术前干预后作为急诊或亚急诊处理,其中静脉注射加压素(垂体后叶素)(100%)、气囊压迫11例(73%)、硬化剂治疗3例(20%),均未能充分控制出血。术后无患者发生静脉曲张再出血。然而,15例患者中有11例(73%)死亡。除2例死于休克继发的不可逆酸中毒外,所有死亡均与肝功能衰竭有关。使用吻合器时遇到6次技术困难,导致3例食管穿孔,均在当时发现并修复。无死亡归因于该并发症。术后早期存活的8例患者中,3例随后死亡,2例死于静脉曲张出血,另1例死于肝功能衰竭。另外2例发生复发性静脉曲张出血,经硬化剂治疗得以控制。随访时间为10至60个月(平均31个月)。尽管EEA吻合器横断食管能控制静脉曲张出血,但用于急性静脉曲张出血时死亡率过高。对于无法从其他治疗方式中获益的特定患者,择期使用似乎有价值。

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