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对于出血性食管静脉曲张是否应采用消融手术?

Should ablative operations be used for bleeding esophageal varices?

作者信息

Keagy B A, Schwartz J A, Johnson G

出版信息

Ann Surg. 1986 May;203(5):463-9. doi: 10.1097/00000658-198605000-00003.

Abstract

To evaluate the long-term success of an ablative procedure for esophageal varices, the clinical results of 60 standardized, non-shunt (Womack) operations performed from 1953-1974 were reviewed. The overall operative mortality in this series was 35%. The 39 patients surviving operation have been followed from 5 to 21 years (mean: 13.3 years). Excluding operative mortality, the absolute 5-year survival rates for Child's classes A, B, and C patients were 100%, 63%, and 33%, respectively. The actuarial survival for all patients was 40% at 5 years, 24% at 10 years, and 15% at 15 years. Although the incidence of recurrent bleeding was 54%, clinical factors predictive for rebleeding could not be identified. A review of a collected series of other ablative operations, with and without esophageal transection, generally reveals unacceptable mortality and rebleeding rates. It is concluded that an ablative operation without esophageal transection should be used only in highly selected patients who do not have appropriate veins suitable for venous shunt.

摘要

为评估食管静脉曲张消融手术的长期疗效,我们回顾了1953年至1974年间进行的60例标准化非分流(沃马克)手术的临床结果。该系列手术的总体手术死亡率为35%。39例术后存活患者的随访时间为5至21年(平均13.3年)。排除手术死亡率后,Child分级A、B和C级患者的5年绝对生存率分别为100%、63%和33%。所有患者的精算生存率在5年时为40%,10年时为24%,15年时为15%。尽管再出血发生率为54%,但无法确定预测再出血的临床因素。对一系列收集的其他消融手术(包括有和没有食管横断术的手术)的回顾显示,其死亡率和再出血率通常难以接受。得出的结论是,不进行食管横断术的消融手术仅应用于没有适合静脉分流的合适静脉的高度选择患者。

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