Scheving L A
Arch Biochem Biophys. 1983 Oct 15;226(2):411-3. doi: 10.1016/0003-9861(83)90309-0.
Sequence similarities are detected between human epidermal growth factor-urogastrone, human pancreatic secretory trypsin inhibitor, and members of the secretin family of gastrointestinal hormones, particularly gastric inhibitory peptide. These similarities suggest a common evolutionary origin for these proteins and a possible functional relationship, as evidenced by the ability of human epidermal growth factor-urogastrone and human pancreatic secretory trypsin inhibitor to form a complex with protease and the ability of human epidermal growth factor-urogastrone and secretin family members to inhibit gastric acid secretion.
在人表皮生长因子 - 尿抑胃素、人胰腺分泌性胰蛋白酶抑制剂与胃肠激素的促胰液素家族成员，尤其是抑胃肽之间检测到了序列相似性。这些相似性表明这些蛋白质有着共同的进化起源以及可能的功能关系，人表皮生长因子 - 尿抑胃素和人胰腺分泌性胰蛋白酶抑制剂与蛋白酶形成复合物的能力以及人表皮生长因子 - 尿抑胃素和促胰液素家族成员抑制胃酸分泌的能力就证明了这一点。
