Ventrucci M, Gullo L, Daniele C, Priori P, Labò G
Am J Gastroenterol. 1983 Dec;78(12):806-9.
Pancreolauryl test (PLT), a tubeless pancreatic function test, was performed in 40 consecutive patients suffering from chronic pancreatitis, in 21 patients with miscellaneous digestive diseases, and in 18 control subjects to assess its diagnostic sensitivity and specificity. N-benzoyl-L-tyrosyl-p-aminobenzoic acid test (PABA test) and secretin-cerulein test were also carried out to compare the diagnostic value of PLT with that of these two pancreatic function tests. PLT was abnormal in 22 of 40 patients with chronic pancreatitis (55%). In particular, pathological results were found in all patients with severe pancreatic insufficiency and only in four of 14 patients with mild to moderate insufficiency. PABA test showed a slightly lower sensitivity in severe insufficiency, and the same sensitivity in mild-moderate insufficiency. PLT was normal in all control subjects and in 17 of 21 patients with nonpancreatic digestive diseases. Its specificity (90%) was slightly higher than that of PABA test (82%). The results indicate that PLT may be used to support a diagnosis of severe pancreatic exocrine insufficiency, while in mild or moderate insufficiency its diagnostic value is limited.
对40例连续性慢性胰腺炎患者、21例患有其他消化系统疾病的患者以及18名对照者进行了胰月桂基试验（PLT），这是一种无管胰腺功能试验，以评估其诊断敏感性和特异性。还进行了N-苯甲酰-L-酪氨酸-p-氨基苯甲酸试验（PABA试验）和促胰液素-胰泌素试验，以比较PLT与这两种胰腺功能试验的诊断价值。40例慢性胰腺炎患者中有22例（55%）PLT异常。特别是，所有严重胰腺功能不全患者均有病理结果，而14例轻度至中度胰腺功能不全患者中只有4例有病理结果。PABA试验在严重胰腺功能不全时敏感性略低，在轻度至中度胰腺功能不全时敏感性相同。所有对照者以及21例非胰腺消化系统疾病患者中的17例PLT正常。其特异性（90%）略高于PABA试验（82%）。结果表明，PLT可用于辅助诊断严重胰腺外分泌功能不全，而在轻度或中度胰腺功能不全时其诊断价值有限。
