前列腺素可使人体血清急性期蛋白增加，而在系统性硬化症中这种增加会减弱。
Prostaglandins cause an increase in serum acute-phase proteins in man, which is diminished in systemic sclerosis.
作者信息
Whicher J T, Bell A M, Martin M F, Marshall L A, Dieppe P A
出版信息
Clin Sci (Lond). 1984 Feb;66(2):165-71. doi: 10.1042/cs0660165.
PMID:6607151
Abstract
The prostaglandin E1 increases the plasma concentration of acute-phase proteins in man and decreases the concentration of certain carrier proteins. This response is greatly diminished in patients with systemic sclerosis, a chronic inflammatory disease leading to fibrosis. These findings pose new questions about the mediation of the acute-phase response and its role in controlling the inflammatory process.
摘要
前列腺素E1可提高人体中急性期蛋白的血浆浓度，并降低某些载体蛋白的浓度。在系统性硬化症（一种导致纤维化的慢性炎症性疾病）患者中，这种反应会大大减弱。这些发现对急性期反应的介导作用及其在控制炎症过程中的作用提出了新的问题。
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