Akins C W, Boucher C A, Pohost G M
Am Heart J. 1984 Feb;107(2):304-9. doi: 10.1016/0002-8703(84)90379-x.
Abnormal interventricular septal motion develops in the majority of patients after cardiac surgery and has been attributed to a variety of causes. This study assesses the role of cardiopulmonary (CP) bypass in the genesis of abnormal septal motion. Twenty-two patients having single coronary artery bypass grafts had septal motion and ejection fraction evaluated preoperatively and postoperatively. The results for 11 patients who had coronary artery bypass grafting (CABG) with CP were compared to those for 11 patients who had grafting without CP bypass. Postoperatively, all 11 patients having bypass grafting with CP bypass had diminution in septal function while 10 of 11 patients having bypass grafting performed without CP bypass had no change or improvement in septal motion (p less than 0.0005). Changes in ejection fraction were not statistically significantly different. This study suggests that abnormal septal motion in patients having CABG is related to CP bypass and/or myocardial preservation techniques.
大多数心脏手术后的患者会出现异常的室间隔运动，其原因多种多样。本研究评估了体外循环（CP）在异常间隔运动发生中的作用。22例接受单支冠状动脉搭桥术的患者在术前和术后接受了间隔运动和射血分数评估。将11例接受CP冠状动脉搭桥术（CABG）患者的结果与11例未接受CP体外循环搭桥术患者的结果进行比较。术后，所有11例接受CP体外循环搭桥术的患者间隔功能均降低，而11例未接受CP体外循环搭桥术的患者中，10例间隔运动无变化或有所改善（p小于0.0005）。射血分数的变化在统计学上无显著差异。本研究表明，接受CABG患者的异常间隔运动与CP体外循环和/或心肌保护技术有关。
