体外细胞反应性：分枝杆菌糖肽、糖脂和肽糖脂对造血集落形成细胞体外生长的影响。
Cellular responsiveness in vitro: the effect of mycobacterial glycopeptides, glycolipids and peptidoglycolipids on the in vitro growth of haemopoietic colony-forming cells.
作者信息
Fleming W A, Stewart-Tull D E, McClure S, McKee A M
出版信息
Immunology. 1984 Mar;51(3):555-61.
Abstract
Incorporation of glycopeptide, glycolipid and peptidoglycolipid preparations from the culture fluid or organisms of a variety of mycobacterial species in suboptimally stimulated cultures of normal mouse bone marrow cells increased the responsiveness of colony-forming cells to colony-stimulating factor, as measured by enhanced colony formation. Possible mechanisms of action and the significance of enhanced colony growth in relation to the mode of action of mycobacterial adjuvants are discussed.
摘要
将来自多种分枝杆菌属的培养液或菌体中的糖肽、糖脂和肽糖脂制剂加入正常小鼠骨髓细胞亚最佳刺激培养物中，通过增强集落形成来测定，集落形成细胞对集落刺激因子的反应性增加。本文讨论了可能的作用机制以及集落生长增强与分枝杆菌佐剂作用方式的关系。
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本文引用的文献
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CORRELATION OF ADJUVANT ACTIVITY AND CHEMICAL STRUCTURE OF WAX D FRACTIONS OF MYCOBACTERIA.分枝杆菌蜡质D组分的佐剂活性与化学结构的相关性
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THE OCCURRENCE OF MURAMIC ACID IN WAX D PREPARATIONS OF MYCOBACTERIA.分枝杆菌蜡D制剂中胞壁酸的存在情况
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A hydrosoluble, adjuvant-active mycobacterial "polysaccharide-peptidoglycan". Preparation by a simple extraction technique of the bacterial cells (strain Peurois).一种水溶性、具有佐剂活性的分枝杆菌“多糖 - 肽聚糖”。通过对细菌细胞（菌株Peurois）采用简单提取技术制备。
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Stimulation of mouse bone marrow colony growth in vitro by conditioned medium.条件培养基对小鼠骨髓集落体外生长的刺激作用。
Aust J Exp Biol Med Sci. 1968 Oct;46(5):607-18. doi: 10.1038/icb.1968.167.
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Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor.小鼠骨髓细胞体外集落形成的研究。II. 集落刺激因子的作用。
J Cell Physiol. 1970 Aug;76(1):89-99. doi: 10.1002/jcp.1040760113.
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Role of adjuvants in the production of delayed hypersensitivity.佐剂在迟发型超敏反应产生中的作用。
Br Med Bull. 1967 Jan;23(1):39-45. doi: 10.1093/oxfordjournals.bmb.a070514.
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Antigen-induced proliferation in vitro of bone marrow precursors of granulocytes and macrophages.抗原诱导的粒细胞和巨噬细胞骨髓前体细胞的体外增殖。
Immunology. 1971 May;20(5):727-38.
10
The effect of synthetic double-stranded polyribonucleotides on haemopoietic colony-forming cells in vitro.合成双链多聚核糖核苷酸对体外造血集落形成细胞的影响。
Immunology. 1971 Nov;21(5):741-50.
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